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The Ultimate Comfort Food: Your New Favorite Italian Sausage Penne Casserole

The Ultimate Comfort Food: Your New Favorite Italian Sausage Penne Casserole

If you’re looking for a crowd-pleasing, comforting meal, this Italian Sausage Penne Casserole is your go-to. Loaded with savory Italian sausage, tender penne pasta, tangy tomatoes, and gooey mozzarella cheese, it’s like lasagna without the fuss.

Ingredients

Scale
  • 16 oz penne pasta

  • 2 lb hot Italian sausage (or sweet/mild)

  • 24 oz shredded mozzarella cheese

  • 1 medium onion, diced

  • 5 cloves garlic, minced

  • 28 oz can diced tomatoes

  • 1½ tsp dried basil

  • 1½ tsp dried oregano

  • Salt and pepper, to taste

  • Non-stick cooking spray

Instructions

  1. Prep casserole dish & oven:
    Preheat oven to 350°F (175°C) and spray a 3-quart casserole dish with non-stick spray.

  2. Cook sausage:
    Remove sausage from casing and crumble into a large skillet. Cook over medium heat until browned. Drain excess grease, reserving 2 tablespoons, and set sausage aside.

  3. Sauté vegetables:
    Add reserved grease to skillet. Sauté onion and garlic until onions are translucent.

  4. Add tomatoes & seasonings:
    Pour in diced tomatoes. Add basil, oregano, salt, and pepper. Cook over medium heat for 5 minutes.

  5. Combine sausage & simmer:
    Return sausage to skillet. Bring mixture to a boil, then cover and simmer on low for 20–30 minutes, stirring occasionally.

  6. Cook pasta:
    Prepare penne according to package directions for al dente. Drain, rinse, and return to pot.

  7. Mix pasta & sauce:
    Stir sausage mixture into pasta. Add half of the mozzarella and stir until melted.

  8. Assemble casserole:
    Place half of the pasta mixture into the prepared casserole dish. Sprinkle with cheese, then add the remaining pasta and top with remaining mozzarella.

  9. Bake:
    Cover with foil and bake 30 minutes until heated through. Remove foil and bake a few more minutes for golden, bubbly cheese.

  10. Serve:
    Slice and serve hot with salad and garlic bread.

Notes

  • Sausage choice: Hot Italian sausage adds a kick; sweet sausage works for a milder flavor.

  • Cheese options: Mix mozzarella with provolone or parmesan for extra richness.

  • Make ahead: Assemble casserole and refrigerate for up to 24 hours before baking.

  • Freezing: Fully cooked and cooled casserole can be frozen in portions for up to 2 months. Reheat covered in the oven.

Nutrition

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